Category Archives: Blog

What’s ERG And Why You Should Care.

Specific protein in prostate tissue increases risk of developing prostate cancer

Men whose biopsied prostate tissue contains a specific protein called ERG have a significantly increased chance of developing prostate cancer, say researchers from Weill Cornell Medical College. This discovery may better guide physicians on how to monitor and proceed with patients deemed to be at risk for developing the disease. ERG is an abnormal combination of two genes that constantly signal cancer cells to grow.

Researchers at Weill Cornell analyzed the biopsies of 461 men in the study. ERG was found in 11 percent of the biopsies. Investigators monitored these patients for three years. They discovered that the number of patients who developed invasive (metastatic) cancer increased with time. In the first year, 15 percent of patients developed the disease. The amount increased to 37 percent in the second year and 53 percent in the third year.

The American Cancer Society estimates that about 238,590 new cases of prostate cancer will have been diagnosed in 2013.

Source: http://weill.cornell.edu/news/releases/wcmc/wcmc_2013/12_03_13.shtml

To Circumcise Or Not?

Uncircumcised Boys Have More Urinary Tract Infections  

Uncircumcised baby boys have a greater chance of developing a urinary tract infection (UTI) regardless if their foreskin is ‘tight’ or not, says a recent study published by the Canadian Medical Association Journal. A tight foreskin is when it is difficult to see the uncircumcised boy’s urethral opening.  However, uncircumcised baby boys’ overall risk of developing the infection is still low — like one out a hundred, says the American Pediatric Association. Circumcised baby boys have a one in 1000 chance of developing a UTI in their first year.

Plastics & Prostate Cancer

Fetal exposure to BPA can increase risk for prostate cancer, says study.

Fetal exposure to a industrial chemical used to make certain plastics can increase risk the risk for prostate cancer later in life, according to a study conducted by the University of Illinois at Chicago. The chemical is bisphenol A or BPA.

Researchers implanted human prostate stem cells into mice and fed them BPA amounts similar with those already seen in pregnant women.  The mice were fed BPA for two weeks and were later given estrogen to mimic rising levels of the female hormone seen in aging men. Tissue was collected two to four months later and analyzed for prostate disease. Researchers discovered one third of the tissue samples had either pre-cancerous lesions or prostate cancer. The study was published online in the journal Endocrinology.

Have A Prostate Cancer Diagnosis From A PSA Screening?

Online tool may help with prostate treatment decisions.

Have you recently been diagnosed with prostate cancer from a PSA screening? Bewildered by what to do? In addition to talking with your urologist and scouring the Internet for reliable medical information, you may want to consider a nomogram. A prostate cancer nomogram is a calculating process, often available online, used to predict one’s prognosis based on certain variables or qualities of his cancer. That ability, in turn, helps determine treatment choices — and avoid overtreatment.  An over diagnosed cancer is one that would not cause symptoms or pose risk to a patient. Some prostate cancers are very slow growing and secondary to other more significant medical cancers. Some academic institutions have developed prostate cancer nomograms that are available online.

Bothered By Recurrent UTIs?

10003295_557477407693566_51107445_nDaily antibiotics effective in preventing recurrent UTI’s in women, says study.

Although cranberry pills, estrogen therapy and acupuncture provide benefit, daily antibiotics are the most effective method to prevent recurrent urinary tract infections in women, according to a new study by researchers at the Los Angeles Biomedical Research Institute (LA BioMed). The study, which was published in the journal Clinical Infectious Diseases, said that more than half of women will suffer from a UTI at some time in their lives, and that they will require antibiotics or some other treatment.   Women who have three or more UTIs per year may require a more proactive approach to prevent recurrence i.e. daily antibiotics.  The LA BioMed study compared the effectiveness of the most commonly used prophylactic measures and found that daily antibiotic use reduced UTI recurrence rate to 0.4 per year.

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